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| 001 | 000045598748 | |
| 005 | 20181214172500 | |
| 008 | 100615s2008 fluaf b 001 0 eng d | |
| 010 | ▼a 2008012853 | |
| 015 | ▼a GBA851687 ▼2 bnb | |
| 020 | ▼a 9781420043181 (hardcover : alk. paper) | |
| 035 | ▼a (OCoLC)ocn214299973 | |
| 035 | ▼a (OCoLC)214299973 ▼z (OCoLC)150372554 | |
| 040 | ▼a DNLM/DLC ▼c DLC ▼d NLM ▼d UKM ▼d BAKER ▼d YDXCP ▼d BTCTA ▼d C#P ▼d BWX ▼d CDX ▼d DLC ▼d 211009 | |
| 050 | 0 0 | ▼a QP517.C45 ▼b .S557 2008 |
| 082 | 0 0 | ▼a 571.7/4 ▼a 571.6 ▼2 22 |
| 084 | ▼a 571.74 ▼2 DDCK | |
| 090 | ▼a 571.74 ▼b S578 | |
| 245 | 0 0 | ▼a Signaling by toll-like receptors / ▼c edited by Gregory W. Konat. |
| 260 | ▼a Boca Raton : ▼b CRC Press, ▼c 2008. | |
| 300 | ▼a xxi, 195 p., [2] p. of plates : ▼b ill. (some col.) ; ▼c 25 cm. | |
| 490 | 1 | ▼a Methods in signal transduction series |
| 504 | ▼a Includes bibliographical references and index. | |
| 505 | 0 | ▼a Assessing the response of cells to TLR stimulation / Kiyoshi Takeda, Masahiro Yamamoto, and Kenya Honda -- TLR ligands in experimental settings their purity and specificity / Min-Fu Tsan -- Analysis of TLR expression, regulation, and signaling / Hui Xiao, Xiaoxia Li, and Derek W. Abbott -- Intracellular trafficking of toll-like receptors / Harald Husebye ... [et al.] -- The role of small RhoGTPases in TLR signaling / Monica Ruse and Ulla G. Knaus -- |
| 505 | 0 | ▼a Use of engineered [beta]-lactamase fragment complementation to detect the associations of toll-like receptors and signaling adaptors / Hyun-Ku Lee and Peter S. Tobias -- Use of toll-like receptor chimeras to dissect mechanisms of receptor localization and signaling / Tadashi Nishiya and Anthony L. DeFranco -- Engagement of toll-like receptors modulates chemokine receptor signaling / Chong-Shan Shi and John H. Kehrl -- Role of toll-like receptor signaling in central nervous system infections / Tammy Kielian -- The influence of injury on toll-like receptor responses / Thomas J. Murphy ... [et al.]. |
| 650 | 0 | ▼a Cellular signal transduction. |
| 650 | 0 | ▼a Natural immunity. |
| 650 | 0 | ▼a Cell receptors. |
| 650 | 0 | ▼a Cellular immunity. |
| 650 | 1 2 | ▼a Toll-Like Receptors ▼x physiology. |
| 650 | 2 2 | ▼a Signal Transduction ▼x physiology. |
| 700 | 1 | ▼a Konat, Gregory W. |
| 776 | 0 8 | ▼i Online version: ▼a Konat, Gregory W. ▼t Signaling by toll-like receptors ▼z 9781420043198 ▼w (211009) 000045964165 |
| 830 | 0 | ▼a Methods in signal transduction. |
| 945 | ▼a KLPA |
소장정보
| No. | 소장처 | 청구기호 | 등록번호 | 도서상태 | 반납예정일 | 예약 | 서비스 |
|---|---|---|---|---|---|---|---|
| No. 1 | 소장처 과학도서관/Sci-Info(2층서고)/ | 청구기호 571.74 S578 | 등록번호 121195984 | 도서상태 대출가능 | 반납예정일 | 예약 | 서비스 |
컨텐츠정보
책소개
The discovery of toll-like receptors (TLRs) spurred the field of innate immunity into a renaissance after many years of neglect. Since then, TLR research has grown at an exponential rate. Taking an integrated methodological approach, Signaling by Toll-Like Receptors offers a comprehensive review of important techniques in molecular biology, cell biology, biochemistry, genetics, and immunology and their critical application to the study of toll-like receptor structure, biological function, and the intracellular signaling triggered by these receptors.
The recent discovery of an ancient family of toll-like receptors (TLRs) in the immune system has substantially enhanced the potential for a variety of therapies, for both failing immune systems, which leaves the body open to infection or over-active ones, which can lead to chronic inflammation. Signaling by Toll-Like Receptors provides a comprehensive review of important techniques in molecular biology, cell biology, biochemistry, genetics, and immunology and their critical application to the study of toll-like receptor structure, biological function, and the intracellular signaling triggered by these receptors, as well as the high promise for uncovering effective pharmaceutical targets.
정보제공 :
목차
Assessing the Response of Cells to TLR Stimulation, K. Takeda, M. Yamamoto, and K. Honda TLR Ligands in Experimental Settings: Their Purity and Specificity, M.F.Tsan Analysis of TLR Expression, Regulation, and Signaling, H. Xiao, X. Li, and D.W. Abbott Intracellular Trafficking of Toll-Like Receptors, H. Husebye, Ø. Halaas, H. Stenmark, and T. Espevik The Role of Small RhoGTPases in TLR Signaling, M. Ruse and U.G. Knaus Use of Engineered β-Lactamase Fragment Complementation to Detect the Associations of Toll-Like Receptors and Signaling Adaptors, H.-K. Lee and P.S. Tobias Use of Toll-Like Receptor Chimeras to Dissect Mechanisms of Receptor Localization and Signaling, T. Nishiya and A.L. DeFranco Engagement of Toll-Like Receptors Modulates Chemokine Receptor Signaling, C.-S. Shi and J.H. Kehrl Role of Toll-Like Receptor Signaling in Central Nervous System Infections, T. Kielian The Influence of Injury on Toll-Like Receptor Responses, T.J. Murphy, A.A. Maung, H.M. Paterson, and J.A. Lederer Index
정보제공 :