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o-Toluidine

o-Toluidine

자료유형
단행본
개인저자
Gregg, N. Dobson, S. Cary, R.
단체저자명
WHO
서명 / 저자사항
o-Toluidine / first draft prepared by N. Gregg, S. Dobson, and R. Cary.
발행사항
Geneva :   World Health Organization,   1998.  
형태사항
iv, 18 p. ; 30 cm.
총서사항
Concise international chemical assessment document,1020-6167 ; no. 7
ISBN
9241530073
일반주기
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."  
"International Programme on Chemical Safety"--Cover.  
서지주기
Includes bibliographical references (p. 13-14).
일반주제명
Toluene --Toxicology. Toluene --Dose-response relationship. Toluene --Environmental aspects. Aniline --Toxicology. Aniline --Dose-response relationship. Aniline --Environmental aspects. Health risk assessment. Toluidines --toxicity. Toluidines --administration dosage. Dose-Response Relationship, Drug. Environmental Exposure. Risk Assessment.
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008 980427s1998 sz b i000 0 eng d
020 ▼a 9241530073
040 ▼a OUN ▼c OUN ▼d 211009
041 0 ▼a eng ▼b frespa
049 0 ▼l 181000929 ▼f UN-W ▼l 131010920 ▼f 의학
082 0 4 ▼a 571.95 ▼2 21
090 ▼a 571.95 ▼b cc ▼c 7
245 0 0 ▼a o-Toluidine / ▼c first draft prepared by N. Gregg, S. Dobson, and R. Cary.
260 ▼a Geneva : ▼b World Health Organization, ▼c 1998.
300 ▼a iv, 18 p. ; ▼c 30 cm.
440 0 ▼a Concise international chemical assessment document, ▼x 1020-6167 ; ▼v no. 7
500 ▼a "Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."
500 ▼a "International Programme on Chemical Safety"--Cover.
504 ▼a Includes bibliographical references (p. 13-14).
546 ▼a Summary in French and Spanish.
650 1 0 ▼a Toluene ▼x Toxicology.
650 1 0 ▼a Toluene ▼x Dose-response relationship.
650 1 0 ▼a Toluene ▼x Environmental aspects.
650 1 0 ▼a Aniline ▼x Toxicology.
650 1 0 ▼a Aniline ▼x Dose-response relationship.
650 1 0 ▼a Aniline ▼x Environmental aspects.
650 1 0 ▼a Health risk assessment.
650 1 2 ▼a Toluidines ▼x toxicity.
650 1 2 ▼a Toluidines ▼x administration dosage.
650 2 2 ▼a Dose-Response Relationship, Drug.
650 2 2 ▼a Environmental Exposure.
650 2 2 ▼a Risk Assessment.
700 1 ▼a Gregg, N.
700 1 ▼a Dobson, S.
700 1 ▼a Cary, R.
710 2 ▼a WHO ▼0 AUTH(211009)64026.
710 2 ▼a World Health Organization.
710 2 ▼a United Nations. ▼b Environment Programme ▼0 AUTH(211009)164396.
710 2 ▼a UNEP.
710 2 ▼a ILO ▼0 AUTH(211009)140147.
710 2 ▼a International Labour Organisation.
710 2 ▼a Inter-Organization Programme for the Sound Management of Chemicals.
710 2 ▼a International Program on Chemical Safety.

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 학술정보관(CDL)/B1 국제기구자료실(UN)/UN-W 청구기호 571.95 cc 7 등록번호 181000929 도서상태 대출불가(자료실) 반납예정일 예약 서비스 M
No. 2 소장처 의학도서관/보존서고4/ 청구기호 571.95 C744 7 등록번호 131010920 도서상태 대출가능 반납예정일 예약 서비스 B M
No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 학술정보관(CDL)/B1 국제기구자료실(UN)/UN-W 청구기호 571.95 cc 7 등록번호 181000929 도서상태 대출불가(자료실) 반납예정일 예약 서비스 M
No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 의학도서관/보존서고4/ 청구기호 571.95 C744 7 등록번호 131010920 도서상태 대출가능 반납예정일 예약 서비스 B M

컨텐츠정보

책소개

A concise assessment of the risks to human health posed by exposure to ortho-toluidine, a chemical used in the manufacture of dyestuffs and, to a lesser extent, in the production of rubber, chemicals and pesticides, and as a curing agent for epoxy resin systems. The document is part of a new series of brief reports aimed at the characterization of hazards and dose-response for exposures to selected industrial chemicals. With this goal in mind, documents in the series focus on studies and findings considered critical for risk characterization. The document is primarily concerned with assessing the carcinogenic risk in occupationally exposed workers. A review of findings from studies in rats and mice, where oral administration of o-toluidine has been linked to a significant increase in the incidence of benign and malignant tumors, supports the conclusion that o-toluidine may act as a genotoxic carcinogen. In humans, limited epidemiological evidence suggests an increased risk of bladder cancer in occupationally exposed workers. In view of evidence that the chemical's carcinogenic action involves a genotoxic mechanism, the assessment was unable to identify a threshold at which exposure would not result in some risk to human health.


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저자소개

World Health Organization(지은이)

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