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With contributions from leading faculty, this new edition provides a clear and concise overview of the most important aspects of pharmacology necessary for a basic understanding of the subject. It reviews the concepts, clinical applications and side effects of pharmacology, emphasising practical applications of the material, whenever possible. A consistent style of writing, and more focused content, help you to better master the essentials.

• Includes online access to Student Consult where you’ll find USMLE-style questions, animations showing the actions of various important toxins, and much more.
• Focuses on the essential aspects of pharmacology for a solid foundation of knowledge in the subject.
• Includes more than 480 full-color illustrations that explain key pharmacologic processes.
• Provides between 4 and 6 USMLE-style self-assessment questions at the end of each chapter?with answers and full explanations in the appendix?that help you prepare for exams and master the material.
• Uses a templated format that promotes more effective and efficient learning.
• Presents color-coded boxes in each chapter that emphasize key points.
• Features a clinical emphasis throughout on both the basic science of pharmacology and its clinical relevance.
• Includes new Gold Standard content on Student Consult with 200 Professional Drug Monographs for additional information on generic and brand names, mechanism of action, pharmacokinetics, indications and dosage, drug interactions, patient education and much more!

• Features a more consistent style of writing?as well as focused, concise content?for enhanced learning of the essentials.
• Presents chapters in a re-arranged order for a more logical approach to learning.
• Includes additional biochemistry and physiology information in the introduction for each section for greater understanding.

Reviews

"This is by far the best edition of this book since section editors have made certain that each chapter is current and follows the same format of therapeutic overview, mechanisms of action, pharmacokinetics, relation of mechanisms of action to clinical response, pharmacovigilance (side effects, clinical problems, and toxicity), and new horizons. The focus is on prototypic drugs with ample use of tables and boxes to provide valuable summaries of how important clinical drugs differ from the prototypic drugs described in detail.

The multicolored figures are both attractive and informative. Each chapter ends with a short, relevant, up-to-date further reading list and a few self-assessment questions. The questions highlight key concepts and drugs covered in the chapter, but are not of the style or complexity of questions currently used on USMLE examinations. Excellent descriptive answers to the self-assessment questions are provided in the appendix. Buyers are also provided with a PIN number for a Student Consult web site which includes complete contents of the book online plus multiple choice questions with feedback as well as other learning enrichments.

This edition is a markedly improved book that rivals Basic and Clinical Pharmacology, 10th edition, by Katzung (McGraw-Hill, 2007), as a leading pharmacology textbook for teaching pharmacology to health professionals. I highly recommend this fifth edition for adoption." - Thomas L. Pazdernik, PhD (University of Kansas Medical Center), from Doody’s Reviews

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Part I:  General Principles, Lynn Wecker
	
1	Pharmacodynamics: Receptors and Concentration-Response Relationships

2	Pharmacokinetics: Absorption, Distribution, Metabolism and Elimination

3	Clinical Pharmacokinetics and Issues in Therapeutics

4	Drug Development, Regulation and Prescription Writing

5	Gene Therapy and Emerging Molecular Therapies

6	Antibodies and Biological Products

7	Herbals and Natural Products

8	Principles of Toxicology
	
Part II: Drugs Affecting the Peripheral Nervous System, Skeletal and Smooth Muscle, Carl Faingold
	
9	Introduction to the Autonomic Nervous System

10	Drugs Affecting the Parasympathetic Nervous System and Autonomic Ganglia

11	Drugs Affecting the Sympathetic Nervous System

12	Skeletal Muscle Relaxants

13	Local Anesthetics

14	Histamine and Antihistamines

15	Eicosanoids

16	Drugs to Treat Asthma and Chronic Obstructive Pulmonary Disease

17	Drugs Affecting Uterine Motility

18	Drugs Affecting the Gastrointestinal System
	
Part III: Drugs Affecting the Cardiovascular, Renal and Circulatory Systems, Stephanie Watts
	
19	Introduction to the Regulation of Cardiovascular Function

20	Antihypertensive Drugs

21	Diuretic Drugs

22	Antiarrhythmic Drugs

23	Drugs to Treat Heart Failure

24	Vasodilators and Nitric Oxide Synthase

25	Lipid-Lowering Drugs and Atherosclerosis

26	Antithrombotic Drugs
	
Part IV: Drugs Affecting the Central Nervous System, Lynn Wecker

27	Introduction to the Central Nervous System

28	Treatment of Parkinson’s and Alzheimer's Diseases

29	Treatment of Psychotic Disorders

30	Treatment of Affective Disorders

31	Treatment of Anxiety and Insomnia

32	Ethanol, Other Alcohols and Drugs for Alcohol Dependence

33	Treatment of Obesity and Eating Disorders

34	Treatment of Seizure Disorders

35	General Anesthetics

36	Drugs to Control Pain

37	Drugs and Substance Abuse, Addiction and Treatment
	
Part V:  Drugs Affecting Endocrine Systems, George Dunaway
	
38	Introduction to Endocrine Pharmacology and Hormones of the Hypothalamus and Pituitary Gland

39	Adrenocorticosteroids

40	Estrogens and Progestins

41	Androgens and Antiandrogens

42	Thyroid and Antithyroid Drugs

43	Insulin and Drugs Used in the Therapy of Diabetes Mellitus

44	Calcium-Regulating Hormones and Other Agents Affecting Bone
	
Part VI:  Chemotherapy of Invading Organisms, Lynn Crespo
	
45	Principles of Antimicrobial Use

46	Bacterial Cell Wall Synthesis Inhibitors

47	Inhibitors of Bacterial Ribosomal Actions

48	Bacterial Folate Antagonists, Fluoroquinolones, and Other Antibacterial Agents

49	Antimycobacterial Agents

50	Antifungal Agents

51	Antiviral Agents

52	Drugs to Treat Parasitic Infections

Part VII:  Chemotherapy of Neoplastic Diseases, Lynn Crespo

53	Principles of Antineoplastic Drug Use

54	Mechanisms of Action of Antineoplastic Drugs

55	Adjuvant Antineoplastic Drugs

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