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The presence of chemicals in our environment is a subject of intense interest owing to the many potential adverse health effects to humans following exposure to these chemicals. The principles and practices of risk assessment are used to assess the associated health risks to provide a scientific and health basis for guidance or regulatory standards development and risk management decision making for public health protection.

This book compiles, discusses, and presents cutting-edge research data and methodology in performing risk assessment of some major chemicals of concern in our environment. It also discusses the complexity of the scientific databases, the available and updated methodology, emerging issues, limitations in knowledge and methods, considerations of developmental and age sensitivities, use of defaults, case samples on results in risk assessment and risk management, and current and future perspectives. The editors are prominent in the field of environmental toxicology, risk assessment, and chemical regulations. This book will appeal to those interested in evaluating the human health effects of exposure to chemicals in the environment and the associated assessments and findings.

Edited by experts in the field, this book compiles, discusses, and presents cutting-edge research data and methodology in performing risk assessment of some major chemicals of concern in our environment. It also discusses the complexity of the scientific databases, the available and updated methodology, emerging issues, limitations in knowledge and methods, considerations of developmental and age sensitivities, use of defaults, case samples on results in risk assessment and risk management, and current and future perspectives.

정보제공 :

Principles and Approaches for Human Health Risk Assessment of Environmental Contaminants; Gloria B. Post

Dose-Response Assessment: Significance in Risk Assessment; Qiyu Jay Zhao

Recent Advances in Cancer Estimation; Andy Salmon

Consideration of Infants and Children in Risk Assessment; Melanie A. Marty

Role of Epidemiology in Drinking Water Risk Assessment; Perry Cohn

Approaches to Using Structure Activity Relationship (SAR) Analysis with Mechanistic Considerations to Assess Carcinogenic Hazard/Risk Potential of Chemical Substances; Yin-Tak Woo and David Y. Lai

The Application of PBPK Modeling, Bayesian Approach, and the Utilization of Markov Chain Monte Carlo Simulation in Risk Assessment; Raymond S. H. Yang, Liesbeth Weijs, Robin McDougall, and Conrad Housand 

Risk Assessment of Trichloroethylene; Patty Wong

Fumigants: Toxicology and Development of Acute Reference Concentrations for Methyl Iodide, Methyl Bromide and Chloropicrin; Lori Lim

Cholinesterase Inhibiting Pesticides: Toxicity, Mechanisms, and Implications for Risk Assessment; Ramesh C. Gupta, Dejan Milatovic, and Anna M. Fan

Mode of Action Toxicity Pathways Demonstrate Developmental Male Reproductive Risk from Endosulfan; Susan Knadle

Evidence on the Carcinogenicity of Butyl Benzyl Phthalate (BBP) and Possible Mechanisms of Action; Jennifer C .Y. Hsieh, Meng Sun, John D. Budroe, Martha S. Sandy, and Lauren Zeise

The Cell and Molecular Biology of Nickel-Induced Cell Transformation and Carcinogenesis; Joseph R. Landolph, Jr., Rini Verma, Jamuna Ramnath, and Farrah Jobling 

Asbestos; Arthur L. Frank

Nanoparticles and Human Health: Physicochemical Considerations; Wesley E. Smith

Nanomaterials: Feasibility and Challenges for Human Health Risk Assessment; Karen Riveles and Danielle Lee

Nanotechnology: Emerging Research and Implications for Health and Policy; Kai Savolainen

Emergency Response: Application of Toxicology and Risk Assessment; Shelley DuTeaux

Toxicology Application in Drug Development; Gene C. Hsu

Application of Toxicology in Food Safety Assessment; Qiong Huang and Xingfen Yang

Chemical Toxicity Testing and Risk Assessment Practice in China; Dan Lou and Zhijun Zhou

Federal-State Toxicology and Risk Analysis Committee (FSTRAC): Communication and Coordination of Toxicology and Risk Assessment of Environmental Contaminants Communication and Coordination of Toxicological Issues and Risk Analysis Activities Relating to Environmental Contaminants; Ambika Bathija and Robert Howd

Challenges and Opportunities for Older Adults; Kathy Sykes, Jackie Moya, Carolina Penalva-Arana, Linda Phillips, and Stephen Gilbert

Occupational Health and Safety Risks for the Aging Worker; Douglas O. Johns and David N. Weissman

Health Implications of Chemicals and Pharmaceutics in an Aging Population; Hsiang-Wen Lin (Margaret)

Water Consumption Data for Derivation of Drinking Water Ingestion Rates for Different Age Groups; Catherine Caraway

Food Consumption Rates for Estimating Exposures to Chemicals in Food; Amy Arcus

Risk Assessment and Critical Thinking; David W. Cragin

Risk Assessment of Chemicals in Drinking Water: Current Concepts and Methodology, Accomplishments, and Future Perspectives; Anna M. Fan, Elaine M. Khan, Bob Howd, and George V. Alexeeff

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