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Mouse models for drug discovery : methods and protocols 2nd ed

Mouse models for drug discovery : methods and protocols 2nd ed

자료유형
단행본
개인저자
Proetzel, Gabriele. Wiles, Michael V.
서명 / 저자사항
Mouse models for drug discovery : methods and protocols / edited by Gabriele Proetzel, Michael V. Wiles.
판사항
2nd ed.
발행사항
New York :   Humana Press :   Springer,   c2016.  
형태사항
xi, 436 p. : ill. (some col.) ; 27 cm.
총서사항
Methods molecular biology,1064-3745 ; 1438
ISBN
149393659X 9781493936595 9781493936618 (eBook)
서지주기
Includes bibliographical references and index.
일반주제명
Animal models in research. Drug development. Drugs --Physiological effect. Mice --Effect of drugs on. Mice --Diseases --Molecular aspects. Drug Discovery --methods. Disease Models, Animal. Mice, Transgenic.
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020 ▼a 9781493936595
020 ▼a 9781493936618 (eBook)
035 ▼a (OCoLC)936532709
040 ▼a YDXCP ▼b eng ▼e rda ▼c YDXCP ▼d BTCTA ▼d GBVCP ▼d OCLCO ▼d IDL ▼d OCLCO ▼d OCLCQ ▼d KUB ▼d 211009
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082 0 4 ▼a 615.580724 ▼2 23
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090 ▼a 615.580724 ▼b M932-2
245 0 0 ▼a Mouse models for drug discovery : ▼b methods and protocols / ▼c edited by Gabriele Proetzel, Michael V. Wiles.
250 ▼a 2nd ed.
260 ▼a New York : ▼b Humana Press : ▼b Springer, ▼c c2016.
300 ▼a xi, 436 p. : ▼b ill. (some col.) ; ▼c 27 cm.
490 1 ▼a Methods molecular biology, ▼x 1064-3745 ; ▼v 1438
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
650 0 ▼a Animal models in research.
650 0 ▼a Drug development.
650 0 ▼a Drugs ▼x Physiological effect.
650 0 ▼a Mice ▼x Effect of drugs on.
650 0 ▼a Mice ▼x Diseases ▼x Molecular aspects.
650 1 2 ▼a Drug Discovery ▼x methods.
650 2 2 ▼a Disease Models, Animal.
650 2 2 ▼a Mice, Transgenic.
655 2 ▼a Laboratory Manuals.
700 1 ▼a Proetzel, Gabriele.
700 1 ▼a Wiles, Michael V.
830 0 ▼a Springer protocols.
830 0 ▼a Methods in molecular biology (Clifton, N.J.) ; ▼v v. 1438.
945 ▼a KLPA

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 과학도서관/Sci-Info(2층서고)/ 청구기호 615.580724 M932-2 등록번호 121237248 도서상태 대출가능 반납예정일 예약 서비스 B M

컨텐츠정보

책소개

1. Genetically Defined Strains in Drug Development and Toxicity Testing

Michael F.W. Festing

2. Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods

Benjamin E. Low, Peter M. Kutny, and Michael V. Wiles

3. Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice

Benjamin E. Low, Rob A. Taft, and Michael V. Wiles

4. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells

Suheyla Hasgur, Ken Edwin Aryee, Leonard D. Shultz, Dale L. Greiner, and Michael A. Brehm

5. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens

Markus von Schaewen, Gabriela Hrebikova, and Alexander Ploss

6. Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies

Derry C. Roopenian, Gregory J. Christianson, Gabriele Proetzel, and Thomas J. Sproule

7. A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics

Benjamin E. Low and Michael V. Wiles

8. Germ-Free Mice Model for Studying Host-Microbial Interactions

Yogesh Bhattarai and Purna Kashyap

9. Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans

David V. Serreze, Marijke Niens, John Kulik, and Teresa P. DiLorenzo

10. Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery

Helene Baribault

11. Cholesterol Absorption and Metabolism

Philip N. Howles

12. Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening

John P. Sundberg, Kathleen A. Silva, Lloyd E. King, Jr, and C. Herbert Pratt

13. Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research

Cong Peng and Shaoguang Li

14. Murine Model for Colitis-Associated Cancer of the Colon

Ashley J. Snider, Agnieszka B. Bialkowska, Amr M. Ghaleb, Vincent W. Yang, Lina M. Obeid, and Yusuf A. Hannun

15. Mouse Models for Studying Depression-Like States and Antidepressant Drugs

Carisa L. Bergner, Amanda N. Smolinsky, Peter C. Hart, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff

16. Experimental Models of Anxiety for Drug Discovery and Brain Research

Peter C. Hart, Carisa L. Bergner, Amanda N. Smolinsky, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff


정보제공 : Aladin

목차

1. Genetically Defined Strains in Drug Development and Toxicity Testing Michael F.W. Festing 2. Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods Benjamin E. Low, Peter M. Kutny, and Michael V. Wiles 3. Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice Benjamin E. Low, Rob A. Taft, and Michael V. Wiles 4. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells Suheyla Hasgur, Ken Edwin Aryee, Leonard D. Shultz, Dale L. Greiner, and Michael A. Brehm 5. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens Markus von Schaewen, Gabriela Hrebikova, and Alexander Ploss 6. Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies Derry C. Roopenian, Gregory J. Christianson, Gabriele Proetzel, and Thomas J. Sproule 7. A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics Benjamin E. Low and Michael V. Wiles 8. Germ-Free Mice Model for Studying Host-Microbial Interactions Yogesh Bhattarai and Purna Kashyap 9. Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans David V. Serreze, Marijke Niens, John Kulik, and Teresa P. DiLorenzo 10. Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery Helene Baribault 11. Cholesterol Absorption and Metabolism Philip N. Howles 12. Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening John P. Sundberg, Kathleen A. Silva, Lloyd E. King, Jr, and C. Herbert Pratt 13. Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research Cong Peng and Shaoguang Li 14. Murine Model for Colitis-Associated Cancer of the Colon Ashley J. Snider, Agnieszka B. Bialkowska, Amr M. Ghaleb, Vincent W. Yang, Lina M. Obeid, and Yusuf A. Hannun 15. Mouse Models for Studying Depression-Like States and Antidepressant Drugs Carisa L. Bergner, Amanda N. Smolinsky, Peter C. Hart, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff 16. Experimental Models of Anxiety for Drug Discovery and Brain Research Peter C. Hart, Carisa L. Bergner, Amanda N. Smolinsky, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff Stacey J. Sukoff Rizzo 18. Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic Christopher Janus, Carolina Hernandez, Victoria deLelys, Hanno Roder, and Hans Welzl 19. Neuromuscular Disease Models and Analysis Robert W. Burgess, Gregory A. Cox, and Kevin L. Seburn 20. Brightfield Imaging and Optical Coherence Tomography of the Mouse Posterior Eye Mark P. Krebs, Mei Xiao, Keith Sheppard, Wanda Hicks, and Patsy M. Nishina 21. Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis Bo Chang


정보제공 : Aladin

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