상세정보

Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood.

In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition.

Topics include:

• Ovarian physiology and the metabolism of xenobiotics
• The effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries
• Ovarian cancer, including endocrine effects and new perspectives on chemoresistance
• Epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals

The first book to focus specifically on ovarian toxicology, this resource is ideal for scientists in academia, regulatory agencies, and industry who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.

Researchers have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. This volume substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition. Topics include ovarian physiology and the metabolism of xenobiotics; the effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries; ovarian cancer; and epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals. The book is essential for those who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.

정보제공 :

Ovarian Function
Ovarian Physiology; Janice M. Bahr and Krista M. Milich
Ovarian Metabolism of Xenobiotics; S. Ganesan, J.A. Madden, and Aileen F. Keating
Brain as a Target for Environmental Toxicants That Alter Ovarian Function; Ralph L. Cooper and Jerome M. Goldman
Xenobiotic-Induced Oxidative Stress; Ulrike Luderer
Ovotoxicity in Small Preantral Follicles; Patricia B. Hoyer and Connie J. Mark-Kappeler

Ovotoxic Chemical Classes
Ovarian Toxicity Caused by Pesticides; Wei Wang, Patrick Hannon, and Jodi A. Flaws
Endocrine Disruptors; Katherine F. Roby
Phthalates; Timothy P. DelValle, Katlyn S. Hafner, and Zelieann R. Craig
Heavy Metals and the Ovary; Sakhila K. Banu
Cigarette Smoking and Ovarian Function; Anne M. Gannon, J.C. Sadeu, S.K. Agarwal, Claude L.

Hughes, and Warren G. Foster
Bisphenol A and the Ovary; Ronit Machtinger and Catherine Racowsky

Ovarian Cancer
Endocrine Effects on Ovarian Cancer; Kendra Hodgkinson and Barbara C. Vanderhyden
New Perspectives in Chemoresistant Ovarian Cancer; Ahmed Y. Ali, Lee Farrand, Ji Young Kim, Akechai Im-Aram, Sanguine Byun, Elaine Lai-Han Leung, Hyong Joo Lee, and Benjamin K. Tsang
Ovarian Cancer; Kathryn Coe, Lisa M. Hess, and G. Marie Swanson

Risk Assessment
Assessing Ovarian Toxicity in Human Health Risk Assessment for Environmental Chemicals and Pharmaceuticals; Susan L. Makris and Wafa Harrouk

Index

정보제공 :