Intro -- HANDBOOK OF DISEASE OUTBREAKS: PREVENTION, DETECTION AND CONTROL -- HANDBOOK OF DISEASE OUTBREAKS: PREVENTION, DETECTION AND CONTROL -- CONTENTS -- PREFACE -- CONTROLLING DISEASE OUTBREAKS: THE CHANGING ROLE OF HOSPITALS -- ABSTRACT -- INTRODUCTION -- PREPARING THE HEALTH CARE SYSTEM -- IMPACT OF AVIAN INFLUENZA IN THE NETHERLANDS -- HOSPITAL CAPACITY -- INTENSIVE CARE UNIT CAPACITY -- WORKFORCE -- GENERAL PRACTITIONERS -- AGE DISTRIBUTION -- UNDERLYING DISEASE AND CO-MORBIDITY -- MITIGATION OF PANDEMIC INFLUENZA -- CONTAINMENT MEASURES FOR PANDEMIC INFLUENZA -- HEALTHCARE SYSTEM READINESS -- INTERNAL PREPARATION -- BUSINESS CONTINUITY -- EXTERNAL PREPARATION -- EVIDENCE-BASED MANAGEMENT -- EVIDENCE FROM FOCUSED MODELLING: A CASE STUDY FROM THE NETHERLANDS -- HEALTHCARE SYSTEM READINESS -- HOSPITAL AND INTENSIVE CARE UNIT CAPACITY -- WORKFORCE -- GENERAL PRACTITIONERS -- AGE DISTRIBUTION -- UNDERLYING DISEASE AND CO-MORBIDITY -- MITIGATION AND CONTAINMENT MEASURES FOR PANDEMIC INFLUENZA -- METHODOLOGICAL CONSIDERATIONS -- CONCLUSION -- ACKNOWLEDGEMENT -- REFERENCES -- CUBAN EPIDEMIC OPTIC NEUROPATHY: AN APPRAISAL OF THE PATHOPHYSIOLOGICAL MECHANISMS -- ABSTRACT -- 1. INTRODUCTION -- 2. CLINICAL SYNDROMES -- 2.1. Optic Neuropathy -- 2.2. Peripheral Neuropathy -- 2.3. Mixed Form -- 3. EPIDEMIOLOGY -- 4. ETIOLOGIC FEATURES -- 4.1. Nutrition -- 4.2. Neurotoxicity -- 4.2.1. Cyanide toxicity -- 4.2.2. Methanol toxicity -- Animal Models -- 4.3. Genetic -- 4.4. Viral Hypothesis -- 5. PATHOPHYSIOLOGICAL CONSIDERATIONS -- 5.1. Oxidative Stress -- 5.2. Excitoxicity -- 5.3. Barrier Systems in CEON -- 6. CONCLUSION -- REFERENCES -- NEW STRATEGIES TO SOLVE AN ANCIENT PROBLEM: PREVENTION OF BUBONIC AND PNEUMONIC PLAGUE USING PLANT-DERIVED VACCINES -- ABSTRACT -- INTRODUCTION -- VACCINES AGAINST BUBONIC AND PNEUMONIC PLAGUE -- 1. CELL-BASED FIRST GENERATION PLAGUE VACCINES -- 1.1. Killed Whole Cell Vaccines (KWCV) -- 1.2. Live Attenuated Vaccines -- 1.3. New Generation of Y. pestis Live Attenuated Vaccines -- 2. ACELLULAR SUBUNIT VACCINES BASED ON F1 AND V ANTIGENS CURRENTLY UNDER DEVELOPMENT AND TRIAL -- 2.1. Escherichia Coli Produced Plague Vaccines -- 2.2. DNA Vaccines for Plague -- 2.3. Particulate Vaccines -- 3. SALMONELLA-BASED PLAGUE VACCINES -- 4. PLANT-DERIVED PLAGUE VACCINES -- 4.1. Stable Expression of Plague Antigens in Tomato Fruit Using Nuclear Transformation -- 4.2. Stable Expression of Plague Antigens in Tobacco Using Chloroplast Transformation -- 4.3. Transient Expression of Plague Antigens in Nicotiana Benthamiana -- CONCLUSION -- REFERENCES -- FROM “NEVER TO HARM” TO HARNESSING PLAGUE: A PARADIGM SHIFT IN PLAGUE ETHICS -- ABSTRACT -- AN OUTLINE PROPOSED -- INEVITABLE SYNERGY: SCIENCE AND MEDICINE TRAPPED IN HISTORY''S FLOW -- HARNESSING PLAGUE: WHEN HARM FIRST BECAME RULE RATHER THAN EXCEPTION -- A BIOETHICAL PRIMER: WHEN DID PHYSICIANS GO FROM “DO NOT HARM” TO UNIT 731? -- DUAL LOYALTY AND PHYSICIANS TODAY: STATE OF THE QUESTION -- .
REFERENCES -- FROM A BURIAL GROUND TO THE DISCOVERY OF AN EPIDEMICAL CRISIS: BIOLOGICAL IDENTITY AND GENOTYPE -- ABSTRACT -- INTRODUCTION -- I. UNUSUAL ARCHÆOLOGICAL ACTS -- II. THE DEAD IN TIMES OF PLAGUE : WHO IS CONCERNED, WHO IS EXCLUDED? -- II.1. Anthropological „Tools‟ : Mortality Profile and Sex Ratio -- II.2. Intrinsic Characteristics of a Confirmed Plague Cemetery -- II.3. Indispensable Access to Archival Data and to Other Confirmed Sites of Plague -- II.4. Re-Evaluation of Ancient Osteological Series -- III. MOLECULAR PALÆOBIOCHEMISTRY RESULTS: AN EMERGING SCIENTIFIC FIELD -- III.1. First Diagnoses of 16th and 18th Century Plague Epidemics -- III.2. Technique Development and First Identification of the Black Death -- III.3. Confirmation of the Black Death and Recognition of Justinian Plague -- IV. ARE ALL PAST PLAGUES CAUSED BY YERSINIA PESTIS ? -- IV.1. Presumed Plague Cemeteries -- IV.2. First Proof of an Antique Plague ? -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES -- MELAMINE POISON: A TEST OF INTER-MEDIA AGENDA SETTING -- INTRODUCTION -- LITERATURE REVIEW -- News Coverage of Disease -- Inter-Media Agenda Setting -- METHODS -- RESULTS OF CONTENT ANALYSES: POISON MILK TOPIC AGENDA -- Press Release Topic Agenda -- Newspaper Topic Agenda -- Internet Portal Topic Agenda -- Internet Bulletin Board Topic Agenda -- Results of Cross-Lagged Correlations of Topic Agenda -- Content Analysis of Affective Attributes -- Results of Cross-Lagged Correlations of Affective Attributes -- CONCLUSION AND DISCUSSION -- REFERENCES -- SOCIAL CONSTRUCTION OF AVIAN FLU INFLUENZA VIRUS -- SOCIAL CONSTRUCTION OF AVIAN FLU INFLUENZA VIRUS -- NEWS AS SOCIAL CONSTRUCTION -- DISEASE AS A SOCIAL CONSTRUCTION -- METHOD -- RESULTS -- Sources -- Frames -- Discourses -- CONCLUSION AND DISCUSSION -- REFERENCES -- SPATIAL AND TEMPORAL PATTERNS OF AUSTRALIAN SUBTROPICAL WHITE SYNDROME AT EAST AUSTRALIAN REEFS: HOST RANGE, PREVALENCE, AND PROGRESSION OF TISSUE NECROSIS -- ABSTRACT -- INTRODUCTION -- METHODS -- Site Selection -- Solitary islands marine park (SIMP) -- Lord howe island (LHI) -- South west rocks (SWR) -- Prevalence of Coral Stress Including ASWS - Belt Transects -- Monitoring Stressed Corals through Time -- Rate-of-spread of ASWS through monitored colonies -- Statistical Analysis -- Seasonal patterns of ASWS within the SIMP -- Cluster analysis -- Correlation analysis -- Rate-of-spread of ASWS through monitored colonies -- RESULTS -- Host Range and Spatial Patterns of ASWS Prevalence -- Solitary islands marine park -- Lord howe island -- South west rocks -- Seasonal Patterns of ASWS within the SIMP -- Patterns of ASWS occurrence -- Monitoring Stressed Corals through Time -- Rate-of-spread of ASWS through monitored colonies -- DISCUSSION -- Host Range and Spatial Patterns of ASWS Prevalence -- Seasonal Patterns of ASWS within the SIMP -- Monitoring Stressed Coral through Time -- Rate-of-spread of ASWS -- CONCLUSION -- ACKNOWLEDGEMENT -- REFERENCES -- DISEASE .
AND TRANSPORT: A COSTLY TICKET AROUND THE WORLD -- ABSTRACT -- INTRODUCTION -- PHYSIOLOGY AND DISEASE -- ANIMAL DISEASES -- HUMAN HEALTH RISKS -- ECONOMIC LOSSES -- GROWING SOCIAL CONCERN -- SHIFTING TOWARDS A CARCASS TRADE -- Prohibition of Long-Distance Transport of Animals for Slaughter -- Introduction of Legislation and Maximum Journey Times -- Partnerships between Governments, Livestock Sector and Animal Welfare Organisations -- CONCLUSION -- REFERENCES -- ASSESSING QUALITY AND VALUE OF PREDICTIVE MODELS FOR DENGUE HEMORRHAGIC FEVER EPIDEMICS -- Abstract -- 1. INTRODUCTION -- 2. METHOD -- 2.1. Data -- 2.1.1. Input-output data for predictive models -- 2.1.2. Hospitalized patient data for assessing forecast value -- 2.2. Models and Prediction Skill -- 2.2.1. Models and their cross-validation -- 2.2.2. Prediction skill assessment -- 2.3. Decision Making Problem -- 2.4. Forecast Value Evaluation -- 3. RESULTS -- 3.1. Epidemic/Non-Epidemic Events -- 3.2. Models Skill -- 3.2.1. Regression model -- 3.2.2. Discriminant model -- 3.3 Models'' Forecast Value -- 3.3.1. Cost of protection -- 3.3.2. Loss due to DHF epidemics -- 4. DISCUSSION -- 5. CONCLUSION -- ACKNOWLEDGEMENT -- REFERENCE -- MATHEMATICAL MODELING OF EPIDEMIC AND EPIZOOTIC PROCESSES OF HEMORRHAGIC FEVER WITH RENAL SYNDROME -- ABSTRACT -- 1. INTRODUCTION -- 2. METHODS -- 3. RESULTS -- 3.1. General Characteristics of Epidemic and Epizootic Processes -- 3.2. Statistical Analysis of the Factual Data -- 3.3. Mathematical Modeling Tasking -- 3.4. Imitation Mathematical Modeling of the “Parasite-Host” System -- 3.4.1. The simplest model -- 3.4.1.1. Brief excursus on model validation technique -- 3.4.2. Considering bank vole population finiteness -- 3.4.3. Considering seasonality -- 3.4.4. Joint considering seasonality and finiteness of bank vole population -- 3.4.5. Considering bank vole population waves -- 4. DISCUSSION -- 4.1. General Characteristic of the Approach Used -- 4.2. Validity of Mathematical Modeling Results -- 4.3. Results of Analysis by Methods of Mathematical Modeling -- 4.4. Practical Importance of Results -- REFERENCES -- MASS MOBILIZATION AND THE ANTI-SCHISTOSOMIASIS CAMPAIGN IN MAOIST CHINA (1955-1960) -- 1. INTRODUCTION -- 2. THE ANTI-SCHISTOSOMIASIS CAMPAIGN AND PUBLIC-HEALTH POLICY IN EARLY MAOIST CHINA -- 3. THE THREE STRATEGIES OF MASS MOBILIZATION -- A. Integration of Schistosomiasis Prevention with Agricultural Development -- B. The Incorporation of Schistosomiasis Prevention into the Patriotic Health Campaign -- C. Integration of the Antischistosomiasis Campaign with Science -- 4. CONCLUSION -- TULAREMIA IS AN INFECTIOUS DISEASE, WHICH TO THIS DAY IS MISTAKEN FOR BUBONIC PLAGUE, AND IN THE ANCIENT WORLD PROBABLY WAS THE MOST FEARED EPIDEMIC -- ABSTRACT -- TULAREMIA, WIDELY DISTRIBUTED, RESEMBLING BUBONIC PLAGUE, YET LITTLE KNOWN -- Tularemia in Ancient Times: Egyptian Epidemics in 1787-1567 BC -- TULAREMIA IN ANCIENT TIMES: LESSONS LEARNED FROM THE “HITTITE PLAGUE” -- .
