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Pre-clinical models : techniques and protocols

Pre-clinical models : techniques and protocols

자료유형
단행본
개인저자
Guest, Paul C.
서명 / 저자사항
Pre-clinical models : techniques and protocols / edited by Paul C. Guest.
발행사항
New York :   Humana Press :   Springer,   c2019.  
형태사항
xiii, 343 p. : ill. (some col.) ; 27 cm.
총서사항
Methods in molecular biology,1064-3745 ; 1916
ISBN
9781493989935 (hbk.) 1493989944 9781493989942 (ebk.)
요약
This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas.
내용주기
A Guide to Mass Spectrometry-based Quantitative Proteomics -- Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes -- The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents -- The Forced Swim Test for Depression-like Behaviour in Rodents -- Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice -- The Nest Building Test in Mice for Assessment of General Well-being -- Mouse Free Dyadic Social Interaction Test -- The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour -- The Y-maze for Assessment of Spatial Working and Reference Memory in Mice -- Maturation of a Human Oligodendrocyte Cell Line -- Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan -- Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur -- Characterization of an Animal Model of Autism and Social Interaction -- Assaying Reproductive Capacity in Female Rodents -- Experimental Model of Hindlimb Suspension-Induced Skeletal Muscle Atrophy in Rodents -- An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes using Flow Cytometry -- Characterization of the db/db Mouse Model of Type 2 Diabetes -- Characterization of the Goto-Kakizaki (GK) Rat Model of Type 2 Diabetes -- Characterization of Human Transplantable Insulinoma Cells -- Preparation of Islets from Rat Pancreas and Assessment of Islet Function -- Cryopreservation of Red Blood Cells -- Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryo-preservation -- Reprogramming of Human Melanocytes and Melanoma cells with Yamanaka Factors -- The Use of 3T3-L1 Murine Preadipocytes as a Model of Adipogenesis -- Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study its Metabolic Role in Cancer Research -- The use of Primary Hepatocytes in Assessment of Drug Safety and Toxicity -- OVA-induced Allergic Airway Inflammation Mouse Model -- Description of Ovariectomy Protocol in Mice -- A Rat Eye Lens Model of Cataract Formation -- A Complete Proteomic Workflow to Study Brain-Related Disorders via Postmortem Tissue -- Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 [beta]-Cell Line- a Preclinical Model for Type 2 Diabetes.
서지주기
Includes bibliographical references and index.
일반주제명
Toxicology. Laboratory animals.
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020 ▼a 9781493989935 (hbk.)
020 ▼a 1493989944
020 ▼a 9781493989942 (ebk.)
035 ▼a (OCoLC)1083347955
040 ▼a AU@ ▼b eng ▼c AU@ ▼d OHS ▼d OCLCF ▼d OCLCO ▼d KUB ▼d 211009
050 4 ▼a RM1-950
082 0 4 ▼a 615 ▼2 23
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090 ▼a 615 ▼b P923
245 0 0 ▼a Pre-clinical models : ▼b techniques and protocols / ▼c edited by Paul C. Guest.
260 ▼a New York : ▼b Humana Press : ▼b Springer, ▼c c2019.
300 ▼a xiii, 343 p. : ▼b ill. (some col.) ; ▼c 27 cm.
490 1 ▼a Methods in molecular biology, ▼x 1064-3745 ; ▼v 1916
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
505 0 ▼a A Guide to Mass Spectrometry-based Quantitative Proteomics -- Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes -- The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents -- The Forced Swim Test for Depression-like Behaviour in Rodents -- Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice -- The Nest Building Test in Mice for Assessment of General Well-being -- Mouse Free Dyadic Social Interaction Test -- The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour -- The Y-maze for Assessment of Spatial Working and Reference Memory in Mice -- Maturation of a Human Oligodendrocyte Cell Line -- Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan -- Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur -- Characterization of an Animal Model of Autism and Social Interaction -- Assaying Reproductive Capacity in Female Rodents -- Experimental Model of Hindlimb Suspension-Induced Skeletal Muscle Atrophy in Rodents -- An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes using Flow Cytometry -- Characterization of the db/db Mouse Model of Type 2 Diabetes -- Characterization of the Goto-Kakizaki (GK) Rat Model of Type 2 Diabetes -- Characterization of Human Transplantable Insulinoma Cells -- Preparation of Islets from Rat Pancreas and Assessment of Islet Function -- Cryopreservation of Red Blood Cells -- Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryo-preservation -- Reprogramming of Human Melanocytes and Melanoma cells with Yamanaka Factors -- The Use of 3T3-L1 Murine Preadipocytes as a Model of Adipogenesis -- Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study its Metabolic Role in Cancer Research -- The use of Primary Hepatocytes in Assessment of Drug Safety and Toxicity -- OVA-induced Allergic Airway Inflammation Mouse Model -- Description of Ovariectomy Protocol in Mice -- A Rat Eye Lens Model of Cataract Formation -- A Complete Proteomic Workflow to Study Brain-Related Disorders via Postmortem Tissue -- Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 [beta]-Cell Line- a Preclinical Model for Type 2 Diabetes.
520 ▼a This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas.
650 0 ▼a Toxicology.
650 0 ▼a Laboratory animals.
700 1 ▼a Guest, Paul C.
830 0 ▼a Methods in molecular biology (Clifton, N.J.) ; ▼v v. 1916.
830 0 ▼a Springer protocols.
945 ▼a KLPA

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 과학도서관/Sci-Info(2층서고)/ 청구기호 615 P923 등록번호 121248855 도서상태 대출가능 반납예정일 예약 서비스 B M

컨텐츠정보

책소개

Part I: Reviews

1. A Guide to Mass Spectrometry-based Quantitative Proteomics

Bradley J. Smith, Daniel Martins-de-Souza, and Mariana Fioramonte

2. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors

Keiko Iwata

3. Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes

Zahra Bahadoran, Parvin Mirmiran, and Asghar Ghasemi

Part II: Protocols

4. The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

5. The Forced Swim Test for Depression-like Behaviour in Rodents

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

6. Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

7. The Nest Building Test in Mice for Assessment of General Well-being

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

8. Mouse Free Dyadic Social Interaction Test

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

9. The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

10. The Y-maze for Assessment of Spatial Working and Reference Memory in Mice

Ann-Katrin Kraeuter, Paul C. Guest, and Zolt?n Sarnyai

11. Maturation of a Human Oligodendrocyte Cell Line

Gabriela Seabra, Val?ria de Almeida, and Daniel Martins-de-Souza

12. Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan

Sumino Yanase, Kayo Yasuda, and Naoki Ishii

13. Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur

Frans Alexander Jacobs, Mari van de Vyver, and William Frank Ferris

14. Characterization of an Animal Model of Autism and Social Interaction

Keiko Iwata

15. Assaying Reproductive Capacity in Female Rodents

Catherine E. Aiken, Jane L. Tarry-Adkins, and Susan E. Ozanne

16. &n


정보제공 : Aladin

목차

Part I: Reviews 1. A Guide to Mass Spectrometry-based Quantitative Proteomics Bradley J. Smith, Daniel Martins-de-Souza, and Mariana Fioramonte 2. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors Keiko Iwata 3. Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes Zahra Bahadoran, Parvin Mirmiran, and Asghar Ghasemi Part II: Protocols 4. The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 5. The Forced Swim Test for Depression-like Behaviour in Rodents Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 6. Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 7. The Nest Building Test in Mice for Assessment of General Well-being Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 8. Mouse Free Dyadic Social Interaction Test Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 9. The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 10. The Y-maze for Assessment of Spatial Working and Reference Memory in Mice Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai 11. Maturation of a Human Oligodendrocyte Cell Line Gabriela Seabra, Valeria de Almeida, and Daniel Martins-de-Souza 12. Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan Sumino Yanase, Kayo Yasuda, and Naoki Ishii 13. Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur Frans Alexander Jacobs, Mari van de Vyver, and William Frank Ferris 14. Characterization of an Animal Model of Autism and Social Interaction Keiko Iwata 15. Assaying Reproductive Capacity in Female Rodents Catherine E. Aiken, Jane L. Tarry-Adkins,and Susan E. Ozanne 16. Experimental Model of Hindlimb Suspension-Induced Skeletal Muscle Atrophy in Rodents Gabriel Nasri Marzuca-Nassr, Kaio Fernando Vitzel, Gilson Masahiro Murata, Jose Luis Marquez, and Rui Curi 17. An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes using Flow Cytometry Yuji Takeda, Hironobu Asao, and Ichiro Wakabayashi 18. Characterization of the db/db Mouse Model of Type 2 Diabetes Paul C Guest and Hassan Rahmoune 19. Characterization of the Goto-Kakizaki (GK) Rat Model of Type 2 Diabetes Paul C. Guest 20. Characterization of Human Transplantable Insulinoma Cells Paul C. Guest 21. Preparation of Islets from Rat Pancreas and Assessment of Islet Function Paul C Guest 22. Cryopreservation of Red Blood Cells Noha AS Alotaibi, Nigel KH Slater, and Hassan Rahmoune 23. Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryo-preservation Noha AS Al-Otaibi, Juliana S Cassoli, Nigel KH Slater, and Hassan Rahmoune 24. Reprogramming of Human Melanocytes and Melanoma cells with Yamanaka Factors Hadiseh Taheri, Umut Cagin, and Acelya Yilmazer 25. The Use of 3T3-L1 Murine Preadipocytes as a Model of Adipogenesis Eleanor Cave and Nigel J Crowther 26. Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study its Metabolic Role in Cancer Research Khanti Rattanapornsompong, Jarunya Ngamkham, Tanit Chavalit, and Sarawut Jitrapakdee 27. The use of Primary Hepatocytes in Assessment of Drug Safety and Toxicity Paul C. Guest 28. OVA-induced Allergic Airway Inflammation Mouse Model Mateus Casaro, Vanessa R. Souza, Fernando A. Oliveira, and Caroline M. Ferreira


정보제공 : Aladin

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