![Ageing [electronic resource] : lessons from C. elegans](https://image.aladin.co.kr/product/8775/16/cover/3319447017_2.jpg)
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| 008 | 190806s2017 sz a ob 001 0 eng d | |
| 020 | ▼a 9783319447018 | |
| 020 | ▼a 9783319447032 (e-book) | |
| 040 | ▼a 211009 ▼c 211009 ▼d 211009 | |
| 050 | 4 | ▼a R-RZ |
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| 084 | ▼a 571.878 ▼2 DDCK | |
| 090 | ▼a 571.878 | |
| 245 | 0 0 | ▼a Ageing ▼h [electronic resource] : ▼b lessons from C. elegans / ▼c Anders Olsen, Matthew S. Gill, editors. |
| 260 | ▼a Cham : ▼b Springer, ▼c c2017. | |
| 300 | ▼a 1 online resource (vi, 439 p.) : ▼b ill. (some col.). | |
| 490 | 1 | ▼a Healthy Ageing and Longevity, ▼x 2199-9007, ▼x 2199-9015 (electronic) |
| 500 | ▼a Title from e-Book title page. | |
| 504 | ▼a Includes bibliographical references and index. | |
| 505 | 0 | ▼a Introduction -- Effects of aging on the basic biology and anatomy of C. elegans -- Dauer Formation and Ageing -- Longevity regulation by insulin/IGF-1 signaling -- Mitochondrial longevity pathways -- Influences of Germline Cells on Organismal Lifespan and Healthspan -- Reproductive Aging -- Nervous System Ageing -- Stress Response Pathways -- Oxidative Stress -- Genome stability and Protein homeostasis and ageing in C. elegans -- Translational control of longevity -- Lipid Metabolism, Lipid Signaling and Longevity -- Autophagy and ageing -- Dietary restriction in C. elegans -- Integration of metabolic signals -- Microbiota, Probiotic Bacteria and Ageing -- The Future of Worm Ageing.-Index. |
| 520 | ▼a This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans. With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public. | |
| 530 | ▼a Issued also as a book. | |
| 538 | ▼a Mode of access: World Wide Web. | |
| 650 | 0 | ▼a Aging ▼x Molecular aspects. |
| 700 | 1 | ▼a Olsen, Anders. |
| 700 | 1 | ▼a Gill, Matthew S. |
| 830 | 0 | ▼a Healthy Ageing and Longevity. |
| 856 | 4 0 | ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-3-319-44703-2 |
| 945 | ▼a KLPA | |
| 991 | ▼a E-Book(소장) |
소장정보
| No. | 소장처 | 청구기호 | 등록번호 | 도서상태 | 반납예정일 | 예약 | 서비스 |
|---|---|---|---|---|---|---|---|
| No. 1 | 소장처 중앙도서관/e-Book 컬렉션/ | 청구기호 CR 571.878 | 등록번호 E14017185 | 도서상태 대출불가(열람가능) | 반납예정일 | 예약 | 서비스 |
컨텐츠정보
책소개
This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans.
With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.
New feature
This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans.
With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.
정보제공 :
목차
Chapter 1 Introduction - Anders Olsen and Matthew S. Gill Chapter 2 Effects of aging on the basic biology and anatomy of C. elegans - Laura A. Herndon, Catherine A. Wolkow, Monica Driscoll and David H. Hall Chapter 3 Dauer Formation and Ageing - Pedro Reis Rodrigues, Kailiang Jia and Matthew S. Gill Chapter 4 Longevity regulation by insulin/IGF-1 signaling - Seon Woo A. An, Murat Artan, Sangsoon Park, Ozlem Altintas, and Seung-Jae V. Lee Chapter 5 Mitochondrial longevity pathways - Alfonso Schiavi and Natascia Ventura Chapter 6 Influences of Germline Cells on Organismal Lifespan and Healthspan - Francis R.G. Amrit and Arjumand Ghazi Chapter 7 Reproductive Aging - Cheng Shi & Coleen T. Murphy Chapter 8 Nervous System Ageing - Claire Benard and Maria Doitsidou Chapter 9 Stress Response Pathways - Dana L. Miller , Joseph Horsman, and Frazer Heinis Chapter 10 Oxidative Stress - Bart P. Braeckman, Patricia Back, Filip Matthijssens Chapter 11 Genome stability and ageing - Aditi U. Gurkar, Matthew S. Gill and Laura J. Niedernhofer Chapter 12 Protein homeostasis and ageing in C. elegans - Silvestre Alavez Chapter 13 Translational control of longevity - Jarod Rollins and Aric Rogers Chapter 14 Lipid Metabolism, Lipid Signaling and Longevity - Jonathon Duffy, Ayse Sena Mutlu, Meng C. Wang Chapter 15 Autophagy and ageing - Malene Hansen Chapter 16 Dietary restriction in C. elegans - Yue Zhang and William B. Mair Chapter 17 Integration of metabolic signals - Dana A. Lynn and Sean P. Curran Chapter 18 Microbiota, Probiotic Bacteria and Ageing - Katrine V. Christensen, Maria G. Morch, Tine H. Morthorst, Simon Lykkemark and Anders Olsen Chapter 19 The Future of Worm Ageing - Gordon J. Lithgow Index
정보제공 :