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Holographic sensors [electronic resource] : doctoral thesis accepted by the University of Cambridge, UK

Holographic sensors [electronic resource] : doctoral thesis accepted by the University of Cambridge, UK

자료유형
E-Book(소장)
개인저자
Yetisen, Ali Kemal.
서명 / 저자사항
Holographic sensors [electronic resource] : doctoral thesis accepted by the University of Cambridge, UK / Ali Kemal Yetisen.
발행사항
Cham :   Springer International Publishing :   Imprint: Springer,   2015.  
형태사항
1 online resource (xviii, 162 p.) : ill. (chiefly col.).
총서사항
Springer theses, recognizing outstanding Ph.D. research,2190-5053, 2190-5061 (electronic)
ISBN
9783319135847
요약
This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions. Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range λpeak ≈ 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices.
일반주기
Title from e-Book title page.  
내용주기
Introduction -- Materials and Methods -- pH-Responsive Holograms -- Divalent Metal Cation Selective Holographic Sensors -- Glucose-Responsive Holograms and Clinical Trials on Diabetic Patients -- A Smartphone Algorithm for the Quantification of Colorimetric Assays -- Final Discussion.
서지주기
Includes bibliographical references.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Biosensors. Holography in medicine. Diagnosis, Noninvasive. Point-of-care testing.
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020 ▼a 9783319135847
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082 0 4 ▼a 610.28/4 ▼2 23
084 ▼a 610.284 ▼2 DDCK
090 ▼a 610.284
100 1 ▼a Yetisen, Ali Kemal.
245 1 0 ▼a Holographic sensors ▼h [electronic resource] : ▼b doctoral thesis accepted by the University of Cambridge, UK / ▼c Ali Kemal Yetisen.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2015.
300 ▼a 1 online resource (xviii, 162 p.) : ▼b ill. (chiefly col.).
490 1 ▼a Springer theses, recognizing outstanding Ph.D. research, ▼x 2190-5053, ▼x 2190-5061 (electronic)
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references.
505 0 ▼a Introduction -- Materials and Methods -- pH-Responsive Holograms -- Divalent Metal Cation Selective Holographic Sensors -- Glucose-Responsive Holograms and Clinical Trials on Diabetic Patients -- A Smartphone Algorithm for the Quantification of Colorimetric Assays -- Final Discussion.
520 ▼a This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions. Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range λpeak ≈ 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Biosensors.
650 0 ▼a Holography in medicine.
650 0 ▼a Diagnosis, Noninvasive.
650 0 ▼a Point-of-care testing.
830 0 ▼a Springer theses, recognizing outstanding Ph.D. research.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-13584-7
945 ▼a KLPA
991 ▼a E-Book(소장)

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