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This book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology. 

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This book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology.

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CONTENTS
1 Medicinal Plants : Ethno-Uses to Biotechnology Era / Aly Farag El Sheikha = 1
2 How Plants Can Contribute to the Supply of Anticancer Compounds / J.F. Buyel = 39
3 Cancer and Biotechnology : A Matchup that Should Never Slowdown / Ala’a Al-Hrout ; Badriya Baig ; Ali Hilal-Alnaqbi ; Amr Amin = 73
4 Plant-Derived Compounds with Anticancer Properties : From Folklore to Practice / Tripti Tewari ; Ruchi Singh ; Vartika Pant ; Ajit Kumar ; Preeti Chaturvedi = 99
5 Anticancer Drugs from Plants / Denise Fernandes Coutinho Moraes ; Ludmilla Santos Silva de Mesquita ; Flavia Maria Mendonça do Amaral ; Maria Nilce de Sousa Ribeiro ; Sonia Malik = 121
6 Cambial Meristematic Cells : A Sustainable Platform for the Production of Plant-Derived Anticancer Drugs / Verity I.P. Loake ; Marisol Ochoa-Villarreal = 143
7 Family Fabaceae : A Boon for Cancer Therapy / Ashita Sharma ; Rajwant Kaur ; Jatinder Kaur Katnoria ; Rajinder Kaur ; Avinash Kaur Nagpal = 157
8 Small Cells for Big Ideas : The Cytotoxic Podophyllotoxin and the Long Journey in Discovering Its Biosynthetic Pathway / Pavlina Sasheva ; Iliana Ionkova = 177
9 Hairy Root Culture for the Production of Useful Secondary Metabolites / Jyothi Abraham ; T. Dennis Thomas = 201
10 Edible Mushrooms and Their In Vitro Culture as a Source of Anticancer Compounds / Bożena Muszyńska ; Katarzyna Kała ; Katarzyna Sułkowska-Ziaja = 231
11 Genomics and Artificial Intelligence Working Together in Drug Discovery and Repositioning : The Advent of Adaptive Pharmacogenomics in Glioblastoma and Chronic Arterial Inflammation Therapies / Glaucia C. Pereira = 253
12 A Multiscale Haemorheological Computer-Based Model of Chronic Inflammation : An In-Depth Investigation of Erythrocytes-Driven Flow Characteristics in Atheroma Development / Glaucia C. Pereira = 283
Index = 321