| 000 | 00000nam u2200205 a 4500 | |
| 001 | 000046041784 | |
| 005 | 20200825102250 | |
| 006 | m d | |
| 007 | cr | |
| 008 | 200814s2014 nyua ob 001 0 eng d | |
| 020 | ▼a 9780387756134 | |
| 040 | ▼a 211009 ▼c 211009 ▼d 211009 | |
| 050 | 0 0 | ▼a RM267 |
| 082 | 0 0 | ▼a 615.7/92 ▼2 23 |
| 084 | ▼a 615.792 ▼2 DDCK | |
| 090 | ▼a 615.792 | |
| 245 | 0 0 | ▼a Fundamentals of antimicrobial pharmacokinetics and pharmacodynamics ▼h [electronic resource] / ▼c Alexander A. Vinks, Hartmut Derendorf, Johan W. Mouton, editors. |
| 260 | ▼a New York, NY : ▼b Springer New York : ▼b Imprint: Springer, ▼c 2014. | |
| 300 | ▼a 1 online resource (ix, 466 p.) : ▼b ill. (some col.). | |
| 500 | ▼a Title from e-Book title page. | |
| 504 | ▼a Includes bibliographical references and index. | |
| 505 | 0 | ▼a Foreword -- Section I: Basic Concepts and Principles -- Introduction to Pharmacodynamics and micrbiology -- In vitro and animal PK/PD model -- MIC and breakpoints -- Principles of applied PK/PD modeling -- Population Pk/PD modeling and its applications to antimicrobials -- Drug resistance and Drug-drug combinations -- Section II: Clinical -- Aminoglycosides -- Beta-lactam antibiotics including continuous infusion -- Macrolides -- Glycopeptides -- Quinolones -- Other. |
| 520 | ▼a Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics is designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader is introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, from basic research to clinical situations. | |
| 530 | ▼a Issued also as a book. | |
| 538 | ▼a Mode of access: World Wide Web. | |
| 650 | 0 | ▼a Anti-infective agents ▼x Physiological transport. |
| 700 | 1 | ▼a Vinks, Alexander A. |
| 700 | 1 | ▼a Derendorf, Hartmut. |
| 700 | 1 | ▼a Mouton, Johan W. |
| 856 | 4 0 | ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-0-387-75613-4 |
| 945 | ▼a KLPA | |
| 991 | ▼a E-Book(소장) |
소장정보
| No. | 소장처 | 청구기호 | 등록번호 | 도서상태 | 반납예정일 | 예약 | 서비스 |
|---|---|---|---|---|---|---|---|
| No. 1 | 소장처 중앙도서관/e-Book 컬렉션/ | 청구기호 CR 615.792 | 등록번호 E14030501 | 도서상태 대출불가(열람가능) | 반납예정일 | 예약 | 서비스 |
