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| 005 | 20181123101746 | |
| 006 | m d | |
| 007 | cr | |
| 008 | 180331s2012 flua ob 001 0 eng d | |
| 020 | ▼a 9781439825853 (e-book) | |
| 020 | ▼a 9781439825846 (hardback) | |
| 035 | ▼a (OCoLC)781312687 | |
| 040 | ▼a FlBoTFG ▼c FlBoTFG ▼e rda ▼d 211009 | |
| 050 | 0 0 | ▼a QP363.2 |
| 082 | 0 0 | ▼a 612.82 ▼2 23 |
| 084 | ▼a 612.82 ▼2 DDCK | |
| 090 | ▼a 612.82 | |
| 245 | 0 0 | ▼a Astrocytes ▼h [electronic resource] : ▼b wiring the brain / ▼c edited by Eliana Scemes, David C. Spray. |
| 260 | ▼a Boca Raton : ▼b CRC Press, ▼c c2012. | |
| 300 | ▼a 1 online resource (xx, 402 p.) : ▼b ill. | |
| 490 | 1 | ▼a Frontiers in neuroscience |
| 500 | ▼a Title from e-Book title page. | |
| 504 | ▼a Includes bibliographical references and index. | |
| 505 | 0 | ▼a section 1. Introduction to cluster A : functional biomarkers at the interface -- section 2. Introduction to cluster B : establishment of functional units : multimodality at the tips -- section 3. CNS pathology : disruption of astrocyte connectivity : introduction. |
| 520 | ▼a Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellular connections and surveys the most current findings on astrocyte activity.The first section of the book identifies major astrocyte biomarkers and describes how they define the different connectivity domains. Next, the book examines the role of these connections. It explains how their function can be manipulated under physiological conditions and how dysfunction of the connectivity leads to aberrant brain performance. The final section explores the alterations of glia that have been observed in specific diseases of the brain. These include epilepsy, autoimmune encephalitis, Alzheimers disease, autism, and major depression. The book identifies key mechanisms responsible for these alterations.An important and emerging field, astrocytes and their functions are critical to neuroscientists and neurologists, both in academia and in industry, particularly in the search for and development of new drugs to combat a variety of diseases affecting the CNS. As research continues to grow in this area, this volume will spur heightened advances and understanding into the effects of these neural cells on a range of pathologies--Provided by publisher. | |
| 530 | ▼a Issued also as a book. | |
| 538 | ▼a Mode of access: World Wide Web. | |
| 650 | 0 | ▼a Astrocytes. |
| 700 | 1 | ▼a Scemes, Eliana. |
| 700 | 1 | ▼a Spray, David C. |
| 830 | 0 | ▼a Frontiers in neuroscience (Boca Raton, Fla.). |
| 856 | 4 0 | ▼u https://oca.korea.ac.kr/link.n2s?url=https://www.taylorfrancis.com/books/9781439825853 |
| 945 | ▼a KLPA | |
| 991 | ▼a E-Book(소장) |
소장정보
| No. | 소장처 | 청구기호 | 등록번호 | 도서상태 | 반납예정일 | 예약 | 서비스 |
|---|---|---|---|---|---|---|---|
| No. 1 | 소장처 중앙도서관/e-Book 컬렉션/ | 청구기호 CR 612.82 | 등록번호 E14007882 | 도서상태 대출불가(열람가능) | 반납예정일 | 예약 | 서비스 |
컨텐츠정보
목차
Front Cover -- Contents -- Series Preface -- Preface: The Astrocyte: A Polarized Cell -- Acknowledgments -- Contributors -- Chapter 1 - Mature Protoplasmic Mammalian Astrocytes: Morphology, Interrelationships, and Implications for Function -- Chapter 2 - Biomarkers of Astrocyte Microdomains: Focus on Gap Junctions, Purinergic Receptors, and Aquaporins -- Chapter 3 - Adhesion Molecules and Their Function in Astrocyte Polarity -- Chapter 4 - Contribution of Astrocytes to CNS Immunity: Roles of Pattern Recognition Receptors (PRRs) -- Chapter 5 - Neuroglial Networks: Glial Wiring Also Matters -- Chapter 6 - Astrocyte-Neuron Communication: What Goes Wrong in Pathology? -- Chapter 7 - Blood–Brain Barrier and the Neural Vascular Unit -- Chapter 8 - Oligodendrocytes: Gateway to the Panglial Syncytium -- Chapter 9 - Microglia and Non-CNS Cells in Paracrine Signaling and CNS Immunity: Effects of Pathogens, Age, and Life History -- Chapter 10 - Astrocytes in Epilepsy -- Chapter 11 - Astrocyte Involvement in the Acquired Demyelinating Diseases -- Chapter 12 - Neuroglia in Alzheimer’s Disease -- Chapter 13 - The Role of Glial Pathology in Autism -- Chapter 14 - Astrocytes in Major Depressive Disorder and Schizophrenia: Pathophysiological and Therapeutic Aspects -- Back Cover -- .